thromboxane a2 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T34862	Thromboxane A2	Rabbit aorta contracting substance,TXA-2,TXA2,TXA 2
	Thromboxane A2, as an unstable intermediate between the prostaglandin endoperoxides and thromboxane B2, is a potent inducer of platelet aggregation and causes vasoconstriction.
T36548	Carbocyclic Thromboxane A2
	Carbocyclic Thromboxane A2 can be used in related research in the field of life sciences. Its product number is T36548 and CAS number is 74034-56-3.
T36208	15(R)-Pinane Thromboxane A2	15(R)-Pinane Thromboxane A2
	15(R)-Pinane thromboxane A2 is the (R)-epimer of pinane thromboxane A2 . 15(R)-PTA2 does not inhibit collagen-induced platelet aggregation (IC50s = 120-130 μM). It does not affect gastric tone in isolated rat gastric fun...
T6236	Ozagrel	OKY-046,Domenan	Thrombin , Prostaglandin Receptor
	Ozagrel (Domenan) is a selective thromboxane A(2) (TXA(2)) synthetase inhibitor with IC50 of 11 nM for rabbit platelet, used for the improvement of postoperative cerebrovascular contraction and accompanying cerebral isch...		Thrombin , Prostaglandin Receptor
T6625	Ozagrel hydrochloride	Ozagrel HCl,OKY-046 HCl	Thrombin , Prostaglandin Receptor
	Ozagrel hydrochloride (OKY-046 HCl) is a selective thromboxane A(2) synthetase inhibitor used for the improvement of postoperative cerebrovascular contraction and accompanying cerebral ischaemia.		Thrombin , Prostaglandin Receptor
T17039	Terbogrel	BIBV 308SE	Prostaglandin Receptor
	Terbogrel is an oral thromboxane A2 receptor antagonist (IC50 is about 10 nM) and thromboxane A2 synthase inhibitor (IC50 is about 10 nM). Terbogrel is an antiplatelet compound that inhibits platelet aggregation and is a...		Prostaglandin Receptor
T12268	NTP42		Prostaglandin Receptor , PPAR
	NTP42 is an antagonist of thromboxane A2 (TXA2) receptor(IC50 of 3.278 nM)		Prostaglandin Receptor , PPAR
T11339L	Furegrelate		PPAR
	FUREGRELATE, a thromboxane A2 (TxA2) synthase inhibitor, blunts the development of pulmonary arterial hypertension in neonatal piglets.		PPAR
T31213	Dazmegrel	UK-38,485,UK 38485,UK 38,485,UK38,485,UK-38485	PPAR
	Dazmegrel (UK 38,485) is a potent and specific thromboxane A2 (TXA2) synthase inhibitor for the prevention of increased whole platelet aggregation in normal pregnancy.		PPAR
T27630	Isbogrel	CV4151,CV-4151,CV 4151	Prostaglandin Receptor
	Isbogrel (CV4151) is a small molecule thromboxane A2 synthase (TXA2 synthase) inhibitor that can be used to study cardiac arrhythmias, transient ischemic attacks and thrombosis.		Prostaglandin Receptor
T11339	Furegrelate sodium	U-63557A	PPAR
	Furegrelate sodium (U-63557A) is a selective thromboxane synthase inhibitor with oral activity. Furegrelate sodium(U-63557A) inhibits thromboxane A2 (TXA2) synthase in human platelet microsomes with an IC50 of 15 nM.		PPAR
T11825	LCB-2853		PPAR
	LCB-2853 is a potent thromboxane A2/prostaglandin H2 (TXA2/PGH2) receptor antagonist with antiplatelet aggregation, antivasospasm, and antithrombotic effects.		PPAR
T68022L	Sulotroban potassium	BM 13177 potassium,Sulotroban potassium(72131-33-0 Free base)	PPAR
	Sulotroban potassium is a small molecule thromboxane A2 receptor (TXA2R) antagonist that can be used to study myocardial infarction and thrombosis.		PPAR
T15049	Daltroban	BM-13505,SKF 96148	PPAR
	Daltroban (SKF 96148) is a specific thromboxane A2 (TXA2) receptor antagonist. Daltroban shows protective effect in reperfusion injury. Daltroban increase intracellular calcium in vascular smooth muscle cells.		PPAR
T0212	Seratrodast	AA 2414,ABT-001	COX , Prostaglandin Receptor , PPAR
	Seratrodast (ABT-001) (INN), a thromboxane A2 (TXA2) receptor (TP receptor) antagonist, is mainly used in the therapy of asthma. It was the first TP receptor antagonist developed as an anti-asthmatic drug and attained ma...		COX , Prostaglandin Receptor , PPAR
T15577	Indobufen	Ibustrin	COX
	Indobufen (Ibustrin) is an inhibitor of platelet aggregation and is a reversible platelet cyclooxygenase (Cox) activity inhibitor. Indobufen suppresses thromboxane A2 (TxA2) synthesis. Indobufen down-regulates tissue fac...		COX
TQ0145	(R)-(+)-Bay-K-8644	(R)-(+)-Bay K 8644	Calcium Channel , PPAR
	(R)-(+)-Bay-K-8644 is a Ca2+ channel agonist, a dihydropyridine agonist that inhibits Ba2+ currents (IBa), induces central respiratory depression in cats, and inhibits platelet activation through competitive antagonism o...		Calcium Channel , PPAR
T68086	Imitrodast		Thrombin
	Imitrodast is a small molecule thromboxane A2 synthase (TXA2 synthase) inhibitor for the treatment of immune system disorders, respiratory disorders, and cardiovascular diseases, and can be used in studies of arterial th...		Thrombin
T0839	Ketoprofen	RP-19583	Apoptosis , COX , MRP
	Ketoprofen (RP-19583) is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic effects. Ketoprofen inhibits the activity of the enzymes cyclo-oxygenas...		Apoptosis , COX , MRP
T1002	Etodolac	Ultradol,AY-24236,Etodolic acid,Lodine	Retinoid Receptor , COX
	Etodolac (AY-24236) inhibits the activity of cyclooxygenase I and II, thereby preventing the formation of prostaglandin which is involved in the induction of pain, fever, and inflammation. Etodolac is a pyranocarboxylic ...		Retinoid Receptor , COX